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Type I collagenase prefers triple-helix collagen as its substrate, with cleavage sites at the N-terminus and C-terminus, while type II collagenase prefers substrates in descending order of affinity: peptides, denatured collagen, and triple-helix collagen, with preferred cleavage sites within the sequence
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Nevertheless, the existing evidence points to several areas where NAC may offer meaningful digestive support
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