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Cuproptosis and serine metabolism blockade triggered by copper-based pRussian blue nanomedicine for enhanced tumor therapy
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Recently, two membrane remodeling enzymes, acyl-CoA synthetase long-chain family member 4 (ACSL4) and lysophosphatidylcholine acyltransferase 3 (LPCAT3), were identified as important drivers of ferroptosis by genome-wide screening and screening with CRISPR/Cas9 technology [46,47,48,49]
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