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Introduction Chronic kidney disease (CKD), affecting approximately 13% of the global population, represents a significant public health burden characterized by progressive loss of renal function ( Enterobacteriaceae and Streptococcus , and decreased beneficial taxa like Prevotella and Roseburia ( Faecalibacterium , Lachnoclostridium , Lactobacillaceae ) and suppressing pathogenic bacteria such as Clostridium innocuum , Enterobacteriales ( CKD is globally prevalent, with gut microbiota dysbiosis increasingly implicated in its pathogenesis

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Symptoms of alcohol overdose include mental confusion, difficulty remaining conscious, vomiting, seizures, trouble breathing, slow heart rate, clammy skin, dulled responses (such as no gag reflex, which prevents choking), and extremely low body temperature